Zaltrap

Drug List

Zaltrap

Drug Name

Zaltrap (Zivaflibercept)

Manufactured By

Sanofi-Aventis U.S. LLC

Drug Savings

NPC's mission is your health. We recognize your need for help when you are applying for discount programs for your prescription medications. We consist of friendly and experienced advocates that not only know how these free and discount programs work, but are ready to help. We are available to take your call and answer any questions you may have as you search for the right program to fit your needs. We can also explain any supporting material you may need to provide as you apply for these programs. If for any reason you are denied, we also are experienced in the best appeals process with a high success rate.

NPC's mission is your health. We recognize your need for help when you are applying for discount programs for your prescription medications. We consist of friendly and experienced advocates that not only know how these free and discount programs work, but are ready to help. We are available to take your call and answer any questions you may have as you search for the right program to fit your needs. We can also explain any supporting material you may need to provide as you apply for these programs. If for any reason you are denied, we also are experienced in the best appeals process with a high success rate.

Treats Disease/Condition

Uses

used in combination with other medications to treat colorectal cancer.

How To Use

Zaltrap is injected into a vein through an IV. A healthcare provider will give you this injection. Zaltrap is usually given every other week. This medicine must be given slowly, and the IV infusion can take at least 1 hour to complete. Zaltrap can cause problems with wound healing, which could result in bleeding or infection. If you need to have any type of surgery, you will need to stop receiving this medicine at least 4 weeks ahead of time. Do not start using the medicine for at least 4 weeks after surgery, or until your surgical incision heals. While using Zaltrap, you may need frequent blood tests. Your blood pressure will also need to be checked often.

Side Effects

Get emergency medical help if you have signs of an allergic reaction to Zaltrap: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Zaltrap can make it easier for you to bleed. Call your doctor or seek emergency medical attention if you have: • easy bruising, unusual bleeding (nose, mouth, vagina, rectum), or any bleeding that will not stop; • signs of bleeding in your digestive tract - severe stomach pain, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or • signs of bleeding in the brain - sudden numbness or weakness (especially on one side of the body), sudden severe headache, problems with speech or balance. Call your doctor at once if you have: • any wound that will not heal; • severe or ongoing vomiting or diarrhea; • chest pain; • confusion, change in mental status, vision loss, seizure (convulsions); • signs of infection - fever, chills, flu-like symptoms, swollen gums, mouth sores, skin sores, rapid heart rate, pale skin, feeling light-headed, pain or burning when you urinate; • dangerously high blood pressure - severe headache, blurred vision, pounding in your neck or ears, nosebleed, anxiety; • dehydration symptoms - feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; • signs of a kidney disorder - puffy eyes, swelling in your ankles or feet, weight gain, urine that looks foamy; or • signs of a fistula (abnormal passageway) in your lower body - rectal pain, foul-smelling vaginal discharge, pain or swelling in your lower stomach, problems with urination or bowel movements. Older adults may be more likely to have severe diarrhea or get dehydrated while receiving Zaltrap. Common Zaltrap side effects may include: • increased blood pressure; • nosebleed; • loss of appetite, stomach pain, diarrhea; • headache, feeling tired; • weight loss; or • abnormal kidney or liver function tests. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Drug Interactions

Other drugs may interact with ziv-aflibercept, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

In Case of Overdose

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

In Case of Missed Dose

Call your doctor for instructions if you miss an appointment for your Zaltrap injection.

Storage

Store Zaltrap vials in a refrigerator at 2 to 8°C (36 to 46°F). Keep the vials in the original outer carton to protect from light.