Drug List


Drug Name

Xalkori (Crizotinib)

Manufactured By

Pfizer, Inc

Drug Savings

Nationwide Prescription Connection (NPC) is an experienced advocacy service that helps connect patients to manufacturer provided free and discount programs. We can help the uninsured, under insured, those in the Medicare gap also known as the "doughnut hole", or even those needing help with expensive co-pays.  Our web site makes it easy for you to enter the medications you are taking, along with some basic patient information, and then finds the program that is right for you.

NPC's mission is your health. We recognize your need for help when you are applying for discount programs for your prescription medications. We consist of friendly and experienced advocates that not only know how these free and discount programs work, but are ready to help. We are available to take your call and answer any questions you may have as you search for the right program to fit your needs. We can also explain any supporting material you may need to provide as you apply for these programs. If for any reason you are denied, we also are experienced in the best appeals process with a high success rate.

Treats Disease/Condition


Crizotinib is used to treat metastatic (cancer that has already spread) non-small cell lung cancer that is caused by a defect in either a gene called anaplastic lymphoma kinase (ALK) or a gene called ROS1. It is an antineoplastic (cancer) agent. Crizotinib interferes with the growth of cancer cells, which are eventually destroyed by the body. This medicine is available only with your doctor's prescription.

How To Use

Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment. Your doctor will tell you how much medicine to use. Do not use more than directed. Swallow the capsule whole. Do not crush, break, chew, or open it. Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

Side Effects

Call your doctor right away if you notice any of these side effects: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, or yellow skin or eyes Fainting, dizziness, or lightheadedness Fast, slow, pounding, or uneven heartbeat Trouble breathing, chest pain, fever, chills, cough If you notice these less serious side effects, talk with your doctor: Change or loss of taste Diarrhea, constipation, nausea Runny or stuffy nose, sore throat Swelling in your hands, ankles, or feet Tiredness Vision changes If you notice other side effects that you think are caused by this medicine, tell your doctor.

Drug Interactions

Some foods and medicines can affect how crizotinib works. Tell your doctor if you are using St John's wort, alfentanil, arsenic trioxide, cisapride, clonidine, cyclosporine, digoxin, dofetilide, fentanyl, pimozide, quinidine, sirolimus, or tacrolimus. Also tell your doctor if you are using blood pressure medicine, medicine to treat HIV/AIDS, medicine to treat an infection or tuberculosis, medicine to treat seizures, medicine to treat depression or mental illness, or an ergot medicine. Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

In Case of Overdose

Seek medical attention

In Case of Missed Dose

If your next dose is more than 6 hours away, take the missed dose as soon as you can. If your next dose is less than 6 hours away, wait until then to use the medicine and skip the missed dose. Do not take extra medicine to make up for the missed dose. If you vomit after you take a dose, do not take an extra dose. Take the next dose at the regular time.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.