Venclexta

Drug List

Venclexta

Drug Name

Venclexta (Venetoclax)

Manufactured By

Genentech, Inc.

Drug Savings

NPC's mission is your health. We recognize your need for help when you are applying for discount programs for your prescription medications. We consist of friendly and experienced advocates that not only know how these free and discount programs work, but are ready to help. We are available to take your call and answer any questions you may have as you search for the right program to fit your needs. We can also explain any supporting material you may need to provide as you apply for these programs. If for any reason you are denied, we also are experienced in the best appeals process with a high success rate.

Nationwide Prescription Connection (NPC) is an experienced advocacy service that helps connect patients to manufacturer provided free and discount programs. We can help the uninsured, under insured, those in the Medicare gap also known as the "doughnut hole", or even those needing help with expensive co-pays.  Our web site makes it easy for you to enter the medications you are taking, along with some basic patient information, and then finds the program that is right for you.

Treats Disease/Condition

Uses

This medication is used to treat a certain type of cancer (chronic lymphocytic leukemia-CLL). Venetoclax is a chemotherapy drug that works by slowing or stopping the growth of cancer cells.

How To Use

Read the Medication Guide provided by your pharmacist before you start taking venetoclax and each time you get a refill. If you have any questions, ask your doctor or pharmacist. To help prevent side effects, drink 6 to 8 glasses (about 56 ounces/1660 milliliters) of water each day, starting 2 days before your first dose, on the day of your first dose, and each time your dose is increased. Take this medication by mouth with a meal and water as directed by your doctor, usually once daily. Swallow the tablets whole. Do not chew, crush, or break the tablets before swallowing. If you vomit soon after taking a dose, do not take another dose on the same day. Take your next dose at the regular time. The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Avoid eating/drinking grapefruit products, Seville oranges (often found in marmalade), or starfruit while using this medication unless your doctor or pharmacist says you may do so safely. These can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.

Side Effects

Diarrhea, nausea, vomiting, tiredness, or headache may occur. Nausea and vomiting can be severe. In some cases, your doctor may prescribe medication to prevent or relieve nausea and vomiting. Eating several small meals, not eating before treatment, or limiting activity may help lessen some of these effects. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Many people using this medication have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk. Tell your doctor right away if you have any serious side effects, such as: easy bruising/bleeding. This medication may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as a sore throat that doesn't go away, fever, chills, cough). Venetoclax sometimes causes side effects due to the rapid destruction of cancer cells (tumor lysis syndrome). To lower your risk, your doctor may add a medication and tell you to drink plenty of fluids. Tell your doctor right away if you have symptoms such as: low back/side pain (flank pain), signs of kidney problems (such as painful urination, pink/bloody urine, change in the amount of urine), muscle spasms/weakness. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Other medications can affect the removal of venetoclax from your body, which may affect how venetoclax works. Examples include azole antifungals (such as itraconazole, ketoconazole), HIV protease inhibitors (such as atazanavir, ritonavir, saquinavir) macrolide antibiotics (such as clarithromycin, erythromycin), rifamycins (such as rifampin, rifabutin), St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.

In Case of Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222.

In Case of Missed Dose

If you miss a dose and it has been less than 8 hours, take it as soon as you remember. If you miss a dose and it has been more than 8 hours, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.