Drug List


Drug Name

Targretin (Bexarotene)

Manufactured By

Valeant Pharmaceuticals North America LLC

Drug Savings

Nationwide Prescription Connection (NPC) is an experienced advocacy service that helps connect patients to manufacturer provided free and discount programs. We can help the uninsured, under insured, those in the Medicare gap also known as the "doughnut hole", or even those needing help with expensive co-pays.  Our web site makes it easy for you to enter the medications you are taking, along with some basic patient information, and then finds the program that is right for you.

NPC's mission is your health. We recognize your need for help when you are applying for discount programs for your prescription medications. We consist of friendly and experienced advocates that not only know how these free and discount programs work, but are ready to help. We are available to take your call and answer any questions you may have as you search for the right program to fit your needs. We can also explain any supporting material you may need to provide as you apply for these programs. If for any reason you are denied, we also are experienced in the best appeals process with a high success rate.

Treats Disease/Condition


Bexarotene is used to treat skin problems from a certain type of cancer (cutaneous T-cell lymphoma-CTCL). It works by slowing or stopping the growth of these cancer cells. Bexarotene belongs to a class of drugs called retinoids (drugs related to vitamin A).

How To Use

Read the Patient Information Leaflet provided by your pharmacist before you start using bexarotene and each time you get a refill. If you have any questions, consult your doctor or pharmacist. This medication is for use on the skin only. Do not apply this medication into mucous membranes such as the eyes, nose, mouth, lips, vagina, tip of the penis, rectum, or anus. Avoid applying to healthy areas of skin because irritation or redness can occur. Wash your hands right away with soap and water before and after using this medication. Cover the affected skin area with a generous layer of gel. Allow the gel to dry for 5 to 10 minutes before covering the area with clothing. This medication is usually applied once every other day for the first week, then increased at weekly intervals to once a day, then twice a day, then 3 times a day, and then finally 4 times a day, or as directed by your doctor. The dosage is based on your medical condition and response to treatment. If side effects occur, your doctor may direct you to apply this medication less often or temporarily stop use until the side effects lessen. Do not cover, bandage, or wrap the treated area unless your doctor directs you to do so. Wait at least 20 minutes after showering or bathing before applying this medication. Use a mild soap when washing the skin to reduce irritation. Avoid showering, bathing, or swimming for at least 3 hours after applying this medication. Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time(s) each day. You may start to see some benefit as early as 4 weeks after starting treatment, but usually you will not get the full benefit until close to a year or more of use. Continue to use this medication and do not stop until your doctor directs you to do so. Since this drug is absorbed through the skin and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication. Learn proper technique for safe handling and disposal of this medicine and its container. Consult your pharmacist.

Side Effects

Pain, redness, irritation, itching, or flaking of the skin may occur at the application site. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Tell your doctor right away if this unlikely but serious side effect occur: sunburn (sun sensitivity). A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Bexarotene can commonly cause a rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe reaction. Therefore, seek immediate medical attention if you develop any rash. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Drug Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. This drug should not be used with the following products because very serious interactions may occur: insect repellents that contain DEET. If you are currently using any product listed above, tell your doctor or pharmacist before starting bexarotene. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: vitamins/supplements that contain vitamin A.

In Case of Overdose

This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222.

In Case of Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.


Store at 2°-25°C (36°-77°F). Avoid exposing to high temperatures and humidity after the bottle is opened. Protect from light.