Drug List


Drug Name

Strensiq (Asfotase alfa)

Manufactured By

Alexion Pharmaceuticals, Inc.

Drug Savings

NPC's mission is your health. We recognize your need for help when you are applying for discount programs for your prescription medications. We consist of friendly and experienced advocates that not only know how these free and discount programs work, but are ready to help. We are available to take your call and answer any questions you may have as you search for the right program to fit your needs. We can also explain any supporting material you may need to provide as you apply for these programs. If for any reason you are denied, we also are experienced in the best appeals process with a high success rate.

Nationwide Prescription Connection (NPC) is an experienced advocacy service that helps connect patients to manufacturer provided free and discount programs. We can help the uninsured, under insured, those in the Medicare gap also known as the "doughnut hole", or even those needing help with expensive co-pays.  Our web site makes it easy for you to enter the medications you are taking, along with some basic patient information, and then finds the program that is right for you.

Treats Disease/Condition


Hypophosphatasia is a rare genetic disorder in which there is a deficiency of an enzyme that helps the body process calcium and phosphorus. This leads to abnormal growth and development of the bones and teeth, including soft or brittle bones, growth problems, and tooth loss.

How To Use

Strensiq is dosed in milligrams based on weight. Strensiq is available as either 1 mg per kg of body weight, 6 times per week, or 2 mg per kg of body weight, 3 times per week. Your doctor will decide which dosage is right for you. If needed, the dose may be increased to 9 mg/kg, 3 times per week, for children with perinatal/infantile-onset hypophosphatasia. If there have been any significant changes in weight for you or your child, your doctor will adjust the dosage. It is important to use Strensiq as described in the Patient Prescribing Information and Instructions for Use , or as instructed by your doctor, nurse, or pharmacist.

Side Effects

Serious allergic (hypersensitivity) reactions. Serious allergic reactions have happened in some people who use Strensiq. Stop using Strensiq and go to the nearest hospital emergency room right away if you have any of the signs and symptoms of a serious allergic reaction, including Difficulty breathing Swelling of your eyes, lips, or tongue Hives Feeling faint Nausea or vomiting Dizziness Itching of your lips, tongue, or throat Skin thickening or pits at the injection site (lipodystrophy). Lipodystrophy at the injection site has happened several months after using Strensiq Calcium buildup in your eyes and kidneys. Your healthcare provider should check your eyes and kidneys while you use Strensiq The most common side effects of Strensiq include local skin injection-site reactions (including red skin patches, bruising, color change, pain, itching, thinning, swelling, pits, and bumps) and calcium buildup in your eyes and kidneys.

Drug Interactions

Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines.

In Case of Overdose

There is no experience with overdose of asfotase alfa.

In Case of Missed Dose


STRENSIQ vials must be stored in the original carton until the time of use under refrigerated conditions at 2°C to 8°C (36°F to 46°F) and protected from light. Once removed from refrigeration, STRENSIQ should be administered within 1 hour. Do not use beyond the expiration date stamped on the carton. DO NOT FREEZE OR SHAKE. Vials are single-use only. Discard any unused product.