RYDAPT

Drug List

RYDAPT

Drug Name

RYDAPT (Midostaurin)

Manufactured By

Novartis Pharmaceuticals Corporation

Drug Savings

NPC's mission is your health. We recognize your need for help when you are applying for discount programs for your prescription medications. We consist of friendly and experienced advocates that not only know how these free and discount programs work, but are ready to help. We are available to take your call and answer any questions you may have as you search for the right program to fit your needs. We can also explain any supporting material you may need to provide as you apply for these programs. If for any reason you are denied, we also are experienced in the best appeals process with a high success rate.

Nationwide Prescription Connection (NPC) is an experienced advocacy service that helps connect patients to manufacturer provided free and discount programs. We can help the uninsured, under insured, those in the Medicare gap also known as the "doughnut hole", or even those needing help with expensive co-pays.  Our web site makes it easy for you to enter the medications you are taking, along with some basic patient information, and then finds the program that is right for you.

Treats Disease/Condition

Uses

Rydapt is an oral prescription medicine used to treat adults: * with newly diagnosed with a certain type of acute myeloid leukemia (AML), in combination with certain chemotherapy medicines * Your healthcare provider will perform a test to make sure Rydapt is right for you. * with aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematological neoplasm (SM-AHN), or mast cell leukemia (MCL) It is not known if this medicine is safe and effective in children.

How To Use

* Take this medicine exactly as your healthcare provider tells you. * Your healthcare provider will tell you how many capsules you need to take. Do not change your dose unless your healthcare provider tells you to. * Your healthcare provider will prescribe medicines to help prevent the nausea and vomiting during treatment. * Take Rydapt two times a day (about every 12 hours apart) * Take the capsules with food. * Do not open or crush the capsules. * If you miss a dose, take your next dose at your scheduled time. Do not take an extra dose to make up for a missed dose. * If you vomit after taking a dose, do not take an extra dose. Take your next dose at your scheduled time.

Side Effects

Rydapt may cause serious side effects, including: * Lung problems. Rydapt may cause lung problems that may lead to death when used alone or in combination with other chemotherapy medicines. Get medical help right away if you have any new or worsening lung symptoms, including cough, chest discomfort, or shortness of breath. The most common side effects of Rydapt in people with AML include: * low white blood cell counts with fever (febrile neutropenia) * nausea * redness, pain or ulcers on the inside your mouth (mucositis) * vomiting * headache * bruising * muscle or bone pain * nose bleeds * device-related infection * high blood sugar levels (hyperglycemia) * upper respiratory tract infection The most common side effects of Rydapt in people with ASM, SM-AHN, or MCL include: * nausea * vomiting * diarrhea * swelling in your hands, feet, or ankles * muscle or bone pain * stomach-area pain * tiredness * upper respiratory tract infection * constipation * fever * headache * trouble breathing Call or inform your healthcare provider if nausea, vomiting or diarrhea occurs, gets worse or does not go away. Rydapt may cause fertility problems in females and males, which may affect your ability to have children. Talk to your healthcare provider if you have concerns about fertility. Your healthcare provider may tell you to decrease your dose, temporarily stop, or completely stop treatment if you develop certain side effects while taking Rydapt. Your healthcare provider will do blood tests to check you for side effects during your treatment. These are not all of the possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Drug Interactions

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

In Case of Overdose

In Case of Missed Dose

If you miss a dose, take your next dose at your scheduled time. Do not take an extra dose to make up for a missed dose. If you vomit after taking a dose, do not take an extra dose. Take your next dose at your scheduled time.

Storage

* Store the capsules at room temperature between 68°F to 77°F (20°C to 25°C). * Keep the capsules in the original package to protect from moisture. Keep all medicines out of the reach of children and pets.