Ravicti

Drug List

Ravicti

Drug Name

Ravicti (Glycerol phenylbutyrate)

Manufactured By

Horizon Pharma Inc.

Drug Savings

Nationwide Prescription Connection (NPC) is an experienced advocacy service that helps connect patients to manufacturer provided free and discount programs. We can help the uninsured, under insured, those in the Medicare gap also known as the "doughnut hole", or even those needing help with expensive co-pays.  Our web site makes it easy for you to enter the medications you are taking, along with some basic patient information, and then finds the program that is right for you.

NPC's mission is your health. We recognize your need for help when you are applying for discount programs for your prescription medications. We consist of friendly and experienced advocates that not only know how these free and discount programs work, but are ready to help. We are available to take your call and answer any questions you may have as you search for the right program to fit your needs. We can also explain any supporting material you may need to provide as you apply for these programs. If for any reason you are denied, we also are experienced in the best appeals process with a high success rate.

Treats Disease/Condition

Uses

RAVICTI is indicated for use as a nitrogen-binding agent for chronic management of adult and pediatric patients ≥2 years of age with urea cycle disorders (UCDs) who cannot be managed by dietary protein restriction and/or amino acid supplementation alone. RAVICTI must be used with dietary protein restriction and, in some cases, dietary supplements (e.g., essential amino acids, arginine, citrulline, protein-free calorie supplements).

How To Use

Ravicti is usually taken 3 times per day. Take with food. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one. Ravicti can also be given through a nasogastric (NG) or gastric feeding tube as follows: After measuring the correct dose in the syringe, attach it to the feeding tube and push the plunger down to empty the syringe into the tube. Then flush the tube with 2 tablespoons of water and allow it to drain. Follow this with 2 more tablespoons of water to wash the contents down.

Side Effects

Adverse reactions occurring in ≥10% of adult patients during short-term treatment (n=44 , 4 weeks) with RAVICTI were diarrhea, flatulence, and headache. Adverse reactions occurring in ≥10% of adult patients during long-term treatment (n=51, 12 months) with RAVICTI were nausea, vomiting, diarrhea, decreased appetite, hyperammonemia, dizziness, headache, and fatigue. Adverse events occurring in ≥10% of pediatric patients during long-term treatment (n=26, 12 months) with RAVICTI were upper abdominal pain, rash, nausea, vomiting, diarrhea, decreased appetite, hyperammonemia, and headache

Drug Interactions

Corticosteroids, valproic acid, or haloperidol: May increase plasma ammonia level. Monitor ammonia levels closely Probenecid: May affect renal excretion of metabolites of RAVICTI, including PAGN and PAA

In Case of Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

In Case of Missed Dose

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Storage