Drug List


Drug Name

Onsolis (Fentanyl Citrate)

Manufactured By

BioDelivery Sciences International, Inc.

Drug Savings

Nationwide Prescription Connection (NPC) is an experienced advocacy service that helps connect patients to manufacturer provided free and discount programs. We can help the uninsured, under insured, those in the Medicare gap also known as the "doughnut hole", or even those needing help with expensive co-pays.  Our web site makes it easy for you to enter the medications you are taking, along with some basic patient information, and then finds the program that is right for you.

NPC's mission is your health. We recognize your need for help when you are applying for discount programs for your prescription medications. We consist of friendly and experienced advocates that not only know how these free and discount programs work, but are ready to help. We are available to take your call and answer any questions you may have as you search for the right program to fit your needs. We can also explain any supporting material you may need to provide as you apply for these programs. If for any reason you are denied, we also are experienced in the best appeals process with a high success rate.

Treats Disease/Condition


To treat "breakthrough" cancer pain that is not controlled by other medications.

How To Use

Use exactly as prescribed. Never use in larger amounts or for longer than recommended by your healthcare provider. Foll the directions on your prescription label. Tell your healthcare provider if it seems to stop working as well in relieving your pain. Use the tongue to wet the inside of the cheek or rinse the mouth with water to wet the area for placement of Onsolis. Open the package immediately prior to use. Place the entire Onsolis film near the tip of a dry finger with the pink side facing up and hold in place. Place the pink side of the Onsolis film against the inside of the cheek. Press and hold the film in place for 5 seconds. The Onsolis film should stay in place on its own after this period. Onsolis film should not be cut or torn before using. The Onsolis film will dissolve within 15 to 30 minutes after application. The film should not be manipulated with the tongue or fingers and eating food should be avoided until the film has dissolved. You may drink liquids after 5 minutes. If your doctor tells you to use more than one Onsolis film at the same time for your breakthrough cancer pain, do not put the films on top of each other. Onsolis films may be placed on either side of your mouth. If you feel dizzy, nauseated, or very sleepy while the film is still in your mouth, spit the medicine out into a sink or toilet and rinse your mouth with water to remove all remaining pieces of the film. Call your doctor for instructions. If your pain does not completely go away, use a second film only if your doctor has approved it. Wait at least 2 hours to treat a new pain episode with Onsolis film. Call your doctor if you have breakthrough pain more than 4 times in one day while using this medicine. Do not stop using Onsolis suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using Onsolis. Keep this medicine out of the reach of children or pets. The amount of fentanyl in each Onsolis film can be fatal to a child or pet who accidentally sucks on or swallows it. Seek emergency medical attention if this happens.

Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction to Onsolis: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. - Stop using Onsolis and call your doctor at once if you have a serious side effect such as: * weak or shallow breathing; * pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating; or * feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin. - Less serious Onsolis side effects may include: * nausea, vomiting, constipation; * dizziness, drowsiness; * headache; * feeling weak or tired; * swelling in your hands or feet; or * pain or mouth sores where the medicine was placed. This is not a complete list of side effects and others may occur. Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088)

Drug Interactions

Do not take Onsolis with any other narcotic pain medications, sedatives, tranquilizers, sleeping pills, muscle relaxers, or other medicines that can make you sleepy or slow your breathing. Dangerous side effects may result. Talk to your healthcare provider about your medications before taking Onsolis.

In Case of Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A fentanyl overdose can be fatal. Overdose symptoms may include extreme weakness or dizziness, pinpoint pupils, cold and clammy skin, weak pulse, fainting, slow breathing (breathing may stop).

In Case of Missed Dose

Since it is used on an as needed basis, you are not likely to miss a dose. Do not take extra medicine to make up the missed dose.


Store Onsolis at room temperature away from moisture and heat. Do not freeze. Keep the medicine its original package until you are ready to take your dose. Keep track of the amount of medicine used from each new bottle. Fentanyl is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.