Drug List


Drug Name

Nexterone (Amiodarone hydrochloride)

Manufactured By

Baxter Healthcare

Drug Savings

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Nationwide Prescription Connection (NPC) is an experienced advocacy service that helps connect patients to manufacturer provided free and discount programs. We can help the uninsured, under insured, those in the Medicare gap also known as the "doughnut hole", or even those needing help with expensive co-pays.  Our web site makes it easy for you to enter the medications you are taking, along with some basic patient information, and then finds the program that is right for you.

Treats Disease/Condition


NEXTERONE is indicated for initiation of treatment and prophylaxis of frequently recurring ventricular fibrillation (VF) and hemodynamically unstable ventricular tachycardia (VT) in patients refractory to other therapy. NEXTERONE also can be used to treat patients with VT/VF for whom oral amiodarone is indicated, but who are unable to take oral medication. During or after treatment with NEXTERONE, patients may be transferred to oral amiodarone therapy. Use NEXTERONE for acute treatment until the patient's ventricular arrhythmias are stabilized. Most patients will require this therapy for 48 to 96 hours, but NEXTERONE may be safely administered for longer periods if necessary.

How To Use

Nexterone is injected into a vein through an IV. Nexterone injection is often given directly into a large vein in the upper chest (central IV line). You will receive this injection in a clinic or hospital setting where your heart can be monitored in case the medicine causes serious side effects. To be sure Nexterone is not causing harmful effects, your blood will need to be tested often. Your thyroid and liver function may also need to be tested, and you may need eye exams and chest x-rays. If you need surgery (including laser eye surgery), tell the surgeon ahead of time that you have received Nexterone injection. This medicine can cause unusual results with certain thyroid tests, even after you stop using it. Tell any doctor who treats you that you have received Nexterone injection. After treatment with Nexterone injection, your doctor may switch you to a tablet form of this medication. Be sure to read the medication guide or patient instructions for amiodarone oral.

Side Effects

Amiodarone takes a long time to completely clear from your body. You may continue to have side effects from amiodarone after you stop using it. It could take up to several months for the medicine to completely clear from your body. Call your doctor at once if you have any of these side effects, even if they occur up to several months after you stop using Nexterone: a new or a worsening irregular heartbeat pattern; fast, slow, or pounding heartbeats; a light-headed feeling, like you might pass out; wheezing, cough, chest pain, trouble breathing, coughing up blood; shortness of breath (even with mild exertion), swelling, rapid weight gain; blurred vision, vision loss, headache or pain behind your eyes, sometimes with vomiting; swelling, pain, redness, or irritation around your IV needle; weight loss, thinning hair, feeling too hot or too cold, increased sweating, irregular menstrual periods, swelling in your neck (goiter); pain in your upper stomach, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or little or no urinating. Common Nexterone side effects may include: low fever; slight dizziness; or mild nausea, vomiting.

Drug Interactions

an antibiotic - azithromycin, ciprofloxacin, clarithromycin, erythromycin, levofloxacin, moxifloxacin, pentamidine, and others; an antidepressant - amitriptyline, citalopram, desipramine, doxepin, imipramine, maprotiline, nortriptyline, and others; cancer medicines; a diuretic or "water pill"; heart rhythm medication - dofetilide, dronedarone, ibutilide, propafenone, sotalol; HIV or AIDS medication - indinavir, nelfinavir, rilpivirine, ritonavir, saquinavir; OR medicine to treat mental illness - chlorpromazine, fluphenazine, haloperidol, lithium, pimozide, promethazine, thioridazine, ziprasidone, and others.

In Case of Overdose

Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

In Case of Missed Dose

Because you will receive Nexterone in a clinical setting, you are not likely to miss a dose.