Drug List


Drug Name

Kyprolis (Carfilzomib)

Manufactured By

Amgen, Inc.

Drug Savings

Nationwide Prescription Connection (NPC) is an experienced advocacy service that helps connect patients to manufacturer provided free and discount programs. We can help the uninsured, under insured, those in the Medicare gap also known as the "doughnut hole", or even those needing help with expensive co-pays.  Our web site makes it easy for you to enter the medications you are taking, along with some basic patient information, and then finds the program that is right for you.

NPC's mission is your health. We recognize your need for help when you are applying for discount programs for your prescription medications. We consist of friendly and experienced advocates that not only know how these free and discount programs work, but are ready to help. We are available to take your call and answer any questions you may have as you search for the right program to fit your needs. We can also explain any supporting material you may need to provide as you apply for these programs. If for any reason you are denied, we also are experienced in the best appeals process with a high success rate.

Treats Disease/Condition


Proteasomes are enzymes found in cells that play an important role in regulating cell function and cell growth by controlling the breakdown of important proteins. As a proteasome inhibitor, Kyprolis blocks the activity of proteasomes and in turn disrupts processes related to the growth and survival of cancer cells.

How To Use

Kyprolis® (carfilzomib, Onyx) is administered as an injection directly into a vein (intravenously, or IV). During each 28-day treatment cycle, Kyprolis is given over 2 consecutive days each week for 3 weeks, followed by 12 days off. Dosing varies slightly depending on whether Kyprolis is given alone or in combination with other agents.

Side Effects

Possible Kyprolis® (carfilzomib, Onyx) side effects depend on an individual’s past health history and on their current stage of multiple myeloma. The most common side effects seen in clinical trials of single-agent Kyprolis were:Fatigue, Low red blood cell count (anemia), Nausea, Low platelet count (thrombocytopenia), Shortness of breath, Diarrhea, Fever The most common serious side effects seen with single-agent Kyprolis in clinical trials were: Low red blood cell count, Low platelet count, Low white blood cell count, Pneumonia

Drug Interactions

The most common adverse reactions occurring in at least 20% of patients treated with KYPROLIS in the combination therapy trials: anemia, neutropenia, diarrhea, dyspnea, fatigue, thrombocytopenia, pyrexia, insomnia, muscle spasm, cough, upper respiratory tract infection, hypokalemia. The most common adverse reactions occurring in at least 20% of patients treated with KYPROLIS in monotherapy trials: anemia, fatigue, thrombocytopenia, nausea, pyrexia, dyspnea, diarrhea, headache, cough, edema peripheral.

In Case of Overdose

Given by a healthcare provider overdose is unexpected

In Case of Missed Dose

call doctor to schedule an appt.


stored by doctor