Gleevec

Drug List

Gleevec

Drug Name

Gleevec (Imatinib)

Manufactured By

Novartis Pharmaceuticals Corporation

Drug Savings

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Treats Disease/Condition

Uses

Gleevec (imatinib) interferes with the growth of some cancer cells. Gleevec is used to treat certain types of leukemia (blood cancer), bone marrow disorders, and skin cancer, or certain tumors of the stomach and digestive system.

How To Use

Gleevec is a pill, taken by mouth, once or twice daily. Gleevec should be taken with a large glass of water, after a meal. The amount of Gleevec that you will receive depends on many factors, including your general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dose and schedule.

Side Effects

The following side effects are common (occurring in greater than 30%) for patients taking Gleevec: Low blood counts. Your white and red blood cells and platelets may temporarily decrease. This can put you at increased risk for infection, anemia and/or bleeding. Nausea and vomiting, Edema (swelling of the face, feet, hands), Muscle cramps and bone pain, Diarrhea, Hemorrhage, Skin rash and Fever These side effects are less common side effects (occurring in about 10-29%) of patients receiving Gleevec: Headache, Fatigue, Joint pain, Indigestion, Abdominal pain, Cough, Shortness of breath, Poor appetite, Constipation, Night sweats, Nose bleeds, Weakness Your fertility, meaning your ability to conceive or father a child, may be affected by Gleevec. Please discuss this issue with your health care provider. A rare, but potentially serious side effect of Gleevec is liver toxicity. There may be elevations in transaminase, bilirubin, and lactate dehydrogenase. Not all side effects are listed above. Some that are rare (occurring in less than 10% of patients) are not listed here. However, you should always inform your health care provider if you experience any unusual symptoms.

Drug Interactions

Many drugs can interact with imatinib. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with Gleevec, especially: Bosentan, Dihydoergotamine or Ergotamine: Fentanyl, Nefazodone, Pimozide, St John's Wart, An Antibiotic, Antifungal medicines, Antiviral Medicines, Blood thinners, heart medicine, Organ rejection medicine, Seizure medicine, Tuberculosis medicine This is not a complete list of Interactions

In Case of Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

In Case of Missed Dose

Take the missed dose as soon as you remember, making sure you also eat a meal and drink a large glass of water. Skip the missed dose if it is almost time for your next dose. Do not take extra medicine to make up the missed dose.

Storage