Coartem

Drug List

Coartem

Drug Name

Coartem (Artmether and Lumefantrine)

Manufactured By

Novartis Pharmaceuticals Corporation

Drug Savings


Nationwide Prescription Connection (NPC) is an experienced advocacy service that helps connect patients to manufacturer provided free and discount programs. We can help the uninsured, under insured, those in the Medicare gap also known as the "doughnut hole", or even those needing help with expensive co-pays.  Our web site makes it easy for you to enter the medications you are taking, along with some basic patient information, and then finds the program that is right for you.


NPC's mission is your health. We recognize your need for help when you are applying for discount programs for your prescription medications. We consist of friendly and experienced advocates that not only know how these free and discount programs work, but are ready to help. We are available to take your call and answer any questions you may have as you search for the right program to fit your needs. We can also explain any supporting material you may need to provide as you apply for these programs. If for any reason you are denied, we also are experienced in the best appeals process with a high success rate.

Treats Disease/Condition

Uses

This medication is used to treat malaria in adults and children. The two ingredients in this medication belong to a class of drugs known as antimalarials. Malaria is an infection caused by mosquito bites received while traveling or living in regions of the world where malaria is common. Malaria parasites enter the body, and live in body tissues such as red blood cells or the liver. This medication is used to kill the malaria parasites living inside red blood cells. In some cases, you may need to take a different medication (such as primaquine) to kill the malaria parasites living in the liver. Both treatments may be needed for a complete cure and to avoid the return of infection (relapse). This product is not used to prevent malaria. The United States Centers for Disease Control provide updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before starting treatment with this medication.

How To Use

Read the Patient Information Leaflet if available from your pharmacist before you start taking this medication and each time you get a refill. If you have any questions regarding the information, ask your doctor or pharmacist. Take this medication by mouth, with food, exactly as prescribed by your doctor. This medication is usually taken twice a day with a meal for 3 days (6 doses) or as directed by your doctor. On your first day of treatment, take your first dose with food, followed by your second dose 8 hours later. Then each day for the next 2 days, take one dose in the morning and one dose in the evening. It is important to take every dose of this medication with food or milk, infant formula, pudding, porridge, or broth. Food helps this medication work better. Tell your doctor if you are unable to eat. If you or your child cannot swallow tablets, the artemether/lumefantrine tablets may be crushed and mixed with one or two teaspoons (5 to 10 milliliters) of water in a clean container at the time your dose is due. Do not crush tablets or mix with water in advance. Follow the dose of medication with food or drink (such as whole milk, formula, pudding, broth, or porridge). If you or your child vomits within 1 to 2 hours of taking this drug, repeat this dose and contact your doctor right away. You will need to make sure you have enough tablets to complete your full course of therapy. If you vomit 2 doses, you may need to be treated with a different medication. The dosage is based on your medical condition, weight, and response to treatment. It is very important to continue taking this medication exactly as prescribed by your doctor. Do not take more or less of this drug than prescribed. Do not skip any doses. Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few doses. Skipping doses or stopping the medication too early may make the infection more difficult to treat and result in a return of the infection. This medication works best when the amount of drug in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. To help you remember, take it at the same times each day.

Side Effects

Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of this medication in your bloodstream. Consult your doctor or pharmacist for more details. Headache, dizziness, loss of appetite, weakness, fever, chills, tiredness, muscle/joint pain, nausea, vomiting, abdominal pain, cough, and trouble sleeping may occur. If any of these effects persist after stopping the medication or if these effects worsen while taking this medication, tell your doctor or pharmacist promptly. Seek immediate medical attention if any of these rare but very serious side effects occur: chest pain, severe dizziness, fainting, fast/irregular/pounding heartbeat. A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Be sure to tell your doctor about all medications you take for malaria within the 4 weeks before, during, and after treatment with artemether/lumefantrine. Some antimalarial drugs (such as halofantrine) should not be used within one month of treatment with artemether/lumefantrine. In some cases a serious (possibly fatal) drug interaction may occur. Many drugs besides artemether/lumefantrine may affect the heart rhythm (QT prolongation), including other antimalarial drugs (such as quinine, quinidine), antiarrhythmic drugs (such as amiodarone, sotalol, procainamide, disopyramide), antipsychotics (such as pimozide, ziprasidone), macrolide antibiotics (such as erythromycin), quinolone antibiotics (such as ciprofloxacin, moxifloxacin), among others. Other medications can affect the removal of artemether/lumefantrine from your body, which may affect how this product works. Examples include some anti-seizure drugs (such as carbamazepine, phenobarbital, phenytoin), azole antifungals (such as ketoconazole, itraconazole), mefloquine, HIV NNRTIs (such as delavirdine, efavirenz), HIV protease inhibitors (such as nelfinavir, ritonavir), rifamycins (such as rifabutin, rifampin), St. John's wort, among others. This medication can speed up or slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include flecainide, certain beta blockers such as metoprolol, certain tricyclic antidepressants (such as amitriptyline and imipramine), among others. This medication may decrease the effectiveness of hormonal birth control such as pills, patch, or ring. This could cause pregnancy. Discuss with your doctor or pharmacist if you should use additional reliable birth control methods while using this medication. Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well.

In Case of Overdose

Symptoms of overdose may include: severe dizziness, fainting, slow/irregular heartbeat. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222.

In Case of Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Do not store in bathroom. Keep all medications away from children and pets.