Drug List


Drug Name

Cathflo (Alteplase (rDNA))

Manufactured By

Genentech, Inc.

Drug Savings

NPC's mission is your health. We recognize your need for help when you are applying for discount programs for your prescription medications. We consist of friendly and experienced advocates that not only know how these free and discount programs work, but are ready to help. We are available to take your call and answer any questions you may have as you search for the right program to fit your needs. We can also explain any supporting material you may need to provide as you apply for these programs. If for any reason you are denied, we also are experienced in the best appeals process with a high success rate.

Nationwide Prescription Connection (NPC) is an experienced advocacy service that helps connect patients to manufacturer provided free and discount programs. We can help the uninsured, under insured, those in the Medicare gap also known as the "doughnut hole", or even those needing help with expensive co-pays.  Our web site makes it easy for you to enter the medications you are taking, along with some basic patient information, and then finds the program that is right for you.

Treats Disease/Condition


Cathflo Activase is a tissue plasminogen activator (tPA). It works by helping to break down unwanted blood clots.

How To Use

Cathflo Activase is usually administered at your doctor's office, hospital, or clinic. If you are using Cathflo Activase at home, carefully follow the procedures taught to you by your health care provider. If Cathflo Activase contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it. Mix Cathflo Activase by swirling gently. Do not shake. Throw away any unused medicine left in the vial. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for selecting an appropriate container and properly disposing of the container when full. If you miss a dose of Cathflo Activase, contact your doctor right away. Ask your health care provider any questions you may have about how to use Cathflo Activase.

Side Effects

All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur: Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or bloody stools; bloody vomit; calf pain or tenderness; changes in vision; chest pain; chills; coughing up blood; difficulty breathing or sudden shortness of breath; fast, slow, or irregular heartbeat; fever; one-sided weakness; redness, swelling, or pain at the catheter site; severe bleeding; severe stomach pain; speech problems or changes; unusual or easy bleeding or bruising.

Drug Interactions

Abciximab, anticoagulants (eg, warfarin, heparin), aspirin, or dipyridamole because the risk of serious side effects, such as bleeding, may be increased Nitrates (eg, nitroglycerin, isosorbide dinitrate) because the effectiveness of Cathflo Activase may be decreased

In Case of Overdose

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include unusual bleeding.

In Case of Missed Dose

If you miss a dose of Cathflo Activase, contact your doctor right away.


Store Cathflo Activase in the refrigerator between 36 and 46 degrees F (2 and 8 degrees C). Store away from heat, moisture, and light. Keep Cathflo Activase, as well as syringes and needles, out of the reach of children and away from pets.