Apligraf Dermal Substitute

Drug List

Apligraf Dermal Substitute

Drug Name

Apligraf Dermal Substitute (Bi-layered skin substitute)

Manufactured By

Organogenesis, Inc

Drug Savings

Nationwide Prescription Connection (NPC) is an experienced advocacy service that helps connect patients to manufacturer provided free and discount programs. We can help the uninsured, under insured, those in the Medicare gap also known as the "doughnut hole", or even those needing help with expensive co-pays.  Our web site makes it easy for you to enter the medications you are taking, along with some basic patient information, and then finds the program that is right for you.

NPC's mission is your health. We recognize your need for help when you are applying for discount programs for your prescription medications. We consist of friendly and experienced advocates that not only know how these free and discount programs work, but are ready to help. We are available to take your call and answer any questions you may have as you search for the right program to fit your needs. We can also explain any supporting material you may need to provide as you apply for these programs. If for any reason you are denied, we also are experienced in the best appeals process with a high success rate.


Treats Disease/Condition


Apligraf is living cell based product for chronic venous leg ulcers and diabetic foot ulcers. Apligraf is supplied as a living, bi-layered skin substitute. Like human skin, Apligraf consists of living cells and structural proteins.

How To Use

Apligraf is supplied as a circular disc approximately 75 mm in diameter and 0.75 mm thick.

Side Effects

The most common health problems experienced were a new foot ulcer, suspected wound infection, a skin tear or cut, skin inflammation, bone infection, rash pain, low blood sugar or high blood sugar, non-wound infection, bruising, swelling, worsening ulcer, and dry skin.

Drug Interactions

No known

In Case of Overdose

If overdose is suspected, contact a poison control center or emergency room right away. US residents can call their local poison control center at 1-800-222-1222.

In Case of Missed Dose

Consult your pharmacist