Alunbrig

Drug List

Alunbrig

Drug Name

Alunbrig (Brigatinib)

Manufactured By

Takeda Pharmaceuticals America, Inc.

Drug Savings


Nationwide Prescription Connection (NPC) is an experienced advocacy service that helps connect patients to manufacturer provided free and discount programs. We can help the uninsured, under insured, those in the Medicare gap also known as the "doughnut hole", or even those needing help with expensive co-pays.  Our web site makes it easy for you to enter the medications you are taking, along with some basic patient information, and then finds the program that is right for you.


NPC's mission is your health. We recognize your need for help when you are applying for discount programs for your prescription medications. We consist of friendly and experienced advocates that not only know how these free and discount programs work, but are ready to help. We are available to take your call and answer any questions you may have as you search for the right program to fit your needs. We can also explain any supporting material you may need to provide as you apply for these programs. If for any reason you are denied, we also are experienced in the best appeals process with a high success rate.

Treats Disease/Condition

Uses

The U.S. FDA has granted Accelerated Approval to Alunbrig (brigatinib), a once-daily oral kinase inhibitor indicated for the treatment of patients with anaplastic lymphoma kinase-positive (ALK+) metastatic non-small cell lung cancer (NSCLC) who have progressed on or are intolerant to crizotinib.

How To Use

* Take this medicine exactly as your healthcare provider tells you to take it. Do not change your dose or stop treatment unless your healthcare provider tells you to. * Your healthcare provider will start you on a low dose (90 mg) for the first seven days of treatment. If you tolerate this dose well, your healthcare provider may increase your dose after the first seven days of treatment. * Your healthcare provider may change your dose, temporarily stop, or permanently stop treatment if you have side effects. * Take Alunbrig one time each day, with or without food. * Swallow the tablets whole. Do not crush or chew the tablets. * If you miss a dose, do not take the missed dose. Take your next dose at your regular time. * If you vomit after taking a dose, do not take an extra dose. Take your next dose at your regular time.

Side Effects

Alunbrig may cause serious side effects, including: * Lung problems. Alunbrig may cause severe or life-threatening swelling (inflammation) of the lungs any time during treatment, and can lead to death. These lung problems happen especially within the first week of treatment. Symptoms may be similar to those symptoms from lung cancer. Tell your healthcare provider right away if you have any new or worsening symptoms, including: -- trouble breathing or shortness of breath -- cough with or without mucous -- chest pain -- fever * High blood pressure (hypertension). Alunbrig may cause high blood pressure. Your healthcare provider will check your blood pressure before starting and during treatment. Tell your healthcare provider right away if you get headaches, dizziness, blurred vision, chest pain or shortness of breath. * Slow heart rate (bradycardia). Alunbrig may cause very slow heartbeats that can be severe. Your healthcare provider will check your heart rate during treatment. Tell your healthcare provider right away if you feel dizzy, lightheaded, or faint during treatment. Tell your healthcare provider if you start to take or have any changes in heart or blood pressure medicines. * Vision problems. Alunbrig may cause vision problems. Your healthcare provider may stop treatment and refer you to an eye specialist if you develop severe vision problems. Tell your healthcare provider right away if you have any loss of vision or any change in vision, including: -- double vision -- light hurting your eyes -- seeing flashes of light -- new or increased floaters -- blurry vision * Muscle pain, tenderness, and weakness (myalgia). Alunbrig may increase the level of an enzyme in your blood called creatine phosphokinase (CPK), which may be a sign of muscle damage. Your healthcare provider will do blood tests to check your blood levels of CPK during treatment. Tell your healthcare provider right away if you get new or worsening signs and symptoms of muscle problems, including unexplained muscle pain or muscle pain that does not go away, tenderness, or weakness. * Inflammation of the pancreas (pancreatitis). Alunbrig may increase enzymes in your blood called amylase and lipase, which may be a sign of pancreatitis. Your healthcare provider will do blood tests to check your pancreatic enzyme blood levels during treatment. Tell your healthcare provider right away if you get new or worsening signs and symptoms of pancreatitis, including upper abdominal pain that may spread to the back and get worse with eating, weight loss, or nausea. * High blood sugar (hyperglycemia). Alunbrig may increase your blood sugar levels. Your healthcare provider will do blood tests to check your blood sugar levels before starting and during treatment. Your healthcare provider may need to start or change your blood sugar medicine to control your blood sugar levels. Tell your healthcare provider right away if you get new or worsening signs and symptoms of hyperglycemia, including: -- feeling very thirsty -- needing to urinate more than usual -- feeling very hungry -- feeling sick to your stomach -- feeling weak or tired -- feeling confused The most common side effects of Alunbrig include: * nausea * fatigue * headache * diarrhea * cough Alunbrig may cause fertility problems in males. This may affect your ability to father a child. Talk to your healthcare provider if you have concerns about fertility. These are not all of the possible side effects. For more information, ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Drug Interactions

In Case of Overdose

In Case of Missed Dose

If you miss a dose, do not take the missed dose. Take your next dose at your regular time.

Storage

Store the tablets at room temperature 20°C to 25°C (68°F to 77°F). Keep all medicines out of the reach of children and pets.